Nylon fiber leukapheresis: associated complement component changes and cranulocytopenia
نویسندگان
چکیده
منابع مشابه
Nylon Fiber Leukapheresis : Associated Complement
The possible role of complement activation in the development of transient granulocytopenia during nylon fiber filtration leukapheresis ( FL) was studied in five normal donors. No changes in hemolytic complement (CH50) titers were observed in the donors’ circulating plasma at any point in the procedure. However, comparison of preand postfilter blood samples drawn 1 mm after donor blood passed t...
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Granulocytes collected by reversible adhesion to nylon wool fiber (NWF) function relatively well in standard in vitro tests; however, they have an abnormally shortened survival time in the circulation. Assuming that this rapid disappearance represents clearance and that recognition by phagocytes is important for such clearance, we used an autologous in vitro cell:cell recognition assay to deter...
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We have investigated the effects of mechanical elution of neutrophils from nylon-wool fiber (NWF) using the scanning electron microscope and biochemical analysis of elution fractions. We have determined that mechanical removal of neutrophils from nylon-wool fiber disrupts neutrophils adherent to nylon-wool fiber and augments release of granules, release of peripheral cytoplasmic fragments, and ...
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The gas holdup behavior in a nylon fiber suspension with various fiber lengths (L = 2, 3, and 6 mm) is investigated. Experiments are performed over a range of superficial gas velocities (Ug≤ 18 cm/s) and a range of fiber mass fractions (0 ≤ C ≤ 1.8%) in a 15.24-cm-diameter semibatch bubble column. Day-to-day variations in the gas holdup create difficulties in interpreting the effect of the fibe...
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The effects of the cationic anesthetic agents tetracaine and lidocaine on granulocyte function, morphology, and adherence to nylon fibers were studied in an attempt to improve current methods of granulocyte collection by filtration leukapheresis (FL). When dissolved in acid-citrate-dextrose (ACD) plasma, these drugs significantly increased granulocyte elution from the fibers in a dose-related f...
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ژورنال
عنوان ژورنال: Blood
سال: 1978
ISSN: 0006-4971,1528-0020
DOI: 10.1182/blood.v51.2.359.359